Recombinant Human PLA2G1B/Phospholipase A2/PLA2/PLA2A/PPLA2,BR

产品属性 Product Attributes

基本信息

别名： PLA2G1B;Phospholipase A2;Group IB phospholipase A2;PLA2;PLA2A;PPLA2
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Supplied as a 0.2 μm filtered solution of 20mM TrisHCl,150mM NaCl,10% Glycerol,pH8.0.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

产品信息

背景说明： Phospholipase A2(PLA2G1B) is a secreted protein which belongs to the phospholipase A2 family.It catalyzes the release of fatty acids from glycero-3-phosphocholines.It catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.This releases glycerophospholipids and arachidonic acid that serve as the precursors of signal molecules.Sequences of pancreatic PLA2G1B enzymes from a variety of mammals have been reported.One striking feature of these enzymes is their close homology to venom phospholipases of snakes.Mice lacking in PLA2G1B are resistant to obesity and diabetes induced by feeding a diabetogenic high-fat/high-carbohydrate diet.Oral supplementation of a diabetogenic diet with the PLA2G1B inhibitor methyl indoxam effectively suppresses diet-induced obesity and diabetes.PLA2G1B inhibition may be a potentially effective oral therapeutic option for treatment of obesity and diabetes.
来源： Human Cells

其它标识

内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

产品介绍 Product Introduction

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注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
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