Recombinant Human Isocitrate Dehydrogenase 1/IDH1 (R132H),BR

产品属性 Product Attributes

基本信息

别名： Isocitrate Dehydrogenase [NADP] Cytoplasmic;IDH;Cytosolic NADP-Isocitrate Dehydrogenase;IDP;NADP(+)-Specific ICDH;Oxalosuccinate Decarboxylase;IDH1;PICD
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Supplied as a 0.2 μm filtered solution of 50mM Tris- HCl, 200mM NaCl, 10% Glycerol, pH 8.0.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

产品信息

背景说明： Isocitrate Dehydrogenase [NADP] Cytoplasmic (IDH1) belongs to the isocitrate and isopropylmalate dehydrogenases family.IDH1 exists as a homodimer，binding one magnesium or manganese ion per subunit.Mutations of IDH1 have been shown to cause metaphyseal chondromatosis with aciduria and are involved in the development of glioma.IDH plays a role in the regeneration of NADPH for intraperoxisomal reductions，such as the conversion of 2，4-dienoyl-CoAs to 3-enoyl-CoAs，as well as in peroxisomal reactions that consume 2-oxoglutarate，namely the α-hydroxylation of phytanic acid.
来源： E.coli

其它标识

内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

产品介绍 Product Introduction

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注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。