Anti-AIFM1 Monoclonal Antibody,BR

产品属性  Product Attributes

基本信息

英文名称：Anti-AIFM1 Monoclonal Antibody

中文名称：凋亡诱导因子, 线粒体相关蛋白1抗体

规格：100ul ; 50ul

宿主：Mouse

克隆类型：Monoclonal Antibody

亚型：IgG2a

克隆号：8H1-B10-A12

交叉反应：Human

应用：ICC ; IF ; WB

稀释比例：WB 1:500-1000. IF 1:50-200. ICC 1:50-200.

抗体信息

靶标：AIFM1

别名：AIF;CMT2D;CMTX4;COWCK;COXPD6;DFNX5;NADMR;NAMSD;PDCD8

背景说明：This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells, and it is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it affects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Mutations in this gene cause combined oxidative phosphorylation deficiency 6, which results in a severe mitochondrial encephalomyopathy. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 10.

Swiss Prot：O95831

Gene ID：9131

亚细胞定位：Cytoplasm Mitochondrion inner membrane Mitochondrion intermembrane space Nucleus perinuclear region

免疫原：Recombinant protein of human AIFM1

理论分子量：67kDa

其它标识

纯化方法：Affinity purification

储存液：PBS with 0.02% sodium azide，0.5% BSA，50% glycerol，pH7.3.

储存条件：Store at -20℃. Avoid freeze / thaw cycles.

产品介绍  Product Introduction

使用前请离心。如有问题请及时联系我们。

Quick spin before use. If you have any questions, please contact us.

注意事项  Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。

2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。

3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。