Recombinant Human Left-right Determination Factor 2,BR

产品属性 Product Attributes

基本信息

别名： Left-right determination factor 2;Endometrial bleeding-associated factor;Left-right determination factor A;Protein lefty-2;Protein lefty-A;Transforming growth factor beta-4;TGF-beta-4;LEFTY2;EBAF;LEFTA;LEFTYA;TGFB4
中文名称: Recombinant Human Left-right Determination Factor 2
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： Left-right determination factor 2(LEFTY2) is a secreted protein which belongs to the TGF-beta family.Lefty was first identified in a screen for undifferentiated cell-specific cDNAs from the P19 mouse embryonal carcinoma cells.Its mRNA expression on the left side of the developing embryo earned the name “Lefty”.The human orthologue was initially identified as Ebaf，Endometrial bleeding associated factor.Lefty contains the six cysteine residues that are conserved among TGF-β related proteins and that are necessary to form the cysteineknot structure.Its function in patterning left-right asymmetry of the developing organ systems such as the heart and lung is consistent in all vertebrate species examined.Lefty acts as an antagonist to Nodal signaling，potentially by competing for binding to a common receptor.It may play a role in endometrial bleeding.
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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