Recombinant Human Parathyroid Hormone/PTH,BR

产品属性 Product Attributes

基本信息

别名： Parathyroid hormone;PTH;Parathormone;Parathyrin;PTH
中文名称: Recombinant Human Parathyroid Hormone/PTH
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： Parathyroid hormone (PTH) is a critical hormone in the regulation of Ca++ homeostasis.Parathyroid hormone is the most important endocrine regulator of calcium and phosphorus concentration in extracellular fluid.This hormone is secreted from cells of the parathyroid glands and finds its major target cells in bone and kidney.Another hormone，parathyroid hormone-related protein，binds to the same receptor as parathyroid hormone and has major effects on development.Like most other protein hormones，parathyroid hormone is synthesized as a preprohormone.After intracellular processing，the mature hormone is packaged with in the Golgi into secretory vesicles，the secreted into blood by exocytosis.In renal epithelium，PTH promotes conversion of Vitamin D to its active form，lowers Ca++ excretion and increases phosphate excretion.PTH also increases hematopoietic stem cell proliferation and mobilization and induces arterial vasodilation by regulating Ca++ influx in PTH1R-expressing arterial smooth muscle.
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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