Recombinant Mouse SLAMF8/SLAM Family Member 8,BR

产品属性 Product Attributes

基本信息

别名： SLAM family member 8;B-lymphocyte activator macrophage expressed;CD353;Slamf8;Blame
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： Mouse SLAM family member 8/SLAMF8 is a single-pass type I membrane protein.It contains one Ig-likeC2-type domain.SLAMF8 is expressed in lymphnode，spleen，thymus and bone marrow.The signaling lymphocyte activation molecule (SLAM) family includes homophilic and heterophilic receptors that modulate both adaptive and innate immune responses.These receptors share a common ectodomain organization: a membrane-proximal immunoglobulin constant domain and a membrane-distal immunoglobulin variable domain that is responsible for ligand recognition.SLAM family of receptors is expressed by a wide range of immune cells.Through their cytoplasmic domain，SLAM family receptors associate with SLAM-associated protein (SAP)-related molecules，a group of cytoplasmic adaptors composed almost exclusively of an SRC homology 2 domain.SLAM family receptors，inassociation with SAP family adaptors，have crucial roles during normal immune reactions in innate and adaptive immune cells.It may play a role in B-lineage commitment and/or modulation of signaling through the B-cell receptor.
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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