Recombinant Cynomolgus PD-L1/B7-H1/CD274/Programmed Cell Death 1 Ligand 1,BR

产品属性 Product Attributes

基本信息

别名： B7-H;B7H1;B7-H1;B7H1PDCD1L1;CD274 antigenMGC142294;CD274 molecule;CD274;PDCD1L1;PDCD1LG1;PDL1;PD-L1;PD-L1B7 homolog 1;PDL1PDCD1 ligand 1;programmed cell death 1 ligand 1;Programmed death ligand 1
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS,pH 7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： CD274，also known as B7-H1 or programmed death ligand 1 (PD-L1)，is a 40 kD type I transmembrane protein and a member of the B7 family within the immunoglobulin receptor superfamily.Programmed death-1 ligand-1 (PD-L1，CD274，B7-H1) has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune responses and peripheral tolerance.By binding to PD1 on activated T-cells and B-cells，PD-L1 may inhibit ongoing T-cell responses by inducing apoptosis and arresting cell-cycle progression.Accordingly，it leads to growth of immunogenic tumor growth by increasing apoptosis of antigen specific T cells and may contribute to immune evasion by cancers.PD-L1 thus is regarded as promising therapeutic target for human autoimmune disease and malignant cancers.
来源： Human Cells

其它标识

溶剂: Dissolve the lyophilized protein in distilled water.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

产品介绍 Product Introduction

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