Recombinant Human DPPIV/CD26/DPP4/Dipeptidyl Peptidase 4,BR

产品属性 Product Attributes

基本信息

别名： Dipeptidyl peptidase 4;ADABP;Adenosine deaminase complexing protein 2;ADCP-2;Dipeptidyl peptidase IV;DPP IV;T-cell activation antigen CD26
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： CD26 is a signal-anchor for type II membrane protein that belongs to the peptidase S9B family.CD26 is expressed specifically in lymphatic vessels but not in blood vessels in the skin，small intestine，esophagus，ovary，breast and prostate glands.It acts as a positive regulator of T-cell coactivation，by binding at least ADA，CAV1，IGF2R，and PTPRC.It’s binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner.Its interaction with ADA also regulates lymphocyte-epithelial cell adhesion.In association with FAP is involved in the pericellular proteolysis of the extracellular matrix (ECM)，the migration and invasion of endothelial cells into the ECM.It may be involved in the promotion of lymphatic endothelial cells adhesion，migration and tube formation.When overexpressed，it enhanced cell proliferation，a process inhibited by GPC3.It acts also as a serine exopeptidase with a dipeptidyl peptidase activity that regulates various physiological processes by cleaving peptides in the circulation，including many chemokines，mitogenic growth factors，neuropeptides and peptide hormones.
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

产品介绍 Product Introduction

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注意事项 Considerations

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