Recombinant Human Rnase T2/Ribonuclease T2,BR

产品属性 Product Attributes

基本信息

别名： Ribonuclease T2;3.1.27.-;Ribonuclease 6;RNASE6PL
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Supplied as a 0.2 μm filtered solution of 20mM TrisHcl, 150mM NaCl,20%Glycerol,pH7.5.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

产品信息

背景说明： RNASET2 (ribonuclease T2) is an enzyme which belongs to the RNase T2 family.It is highly expressed in the temporal lobe and fetal brain.RNASET2 gene is a novel member of the Rh/T2/S-glycoprotein class of extracellular ribonucleases.This protein can be inhibited by Zn2+ and Cu2+.It has ribonuclease activity，with higher activity at acidic pH and is probably involved in lysosomal degradation of ribosomal RNA.Defects in RNASET2 are the cause of leukoencephalopathy cystic without megalencephaly.An infantile-onset syndrome of cerebral leukoencephalopathy.Affected newborns develop microcephaly and neurologic abnormalities including psychomotor impairment，seizures and sensorineural hearing impairment.The brain shows multifocal white matter lesions，anterior temporal lobe subcortical cysts，pericystic abnormal myelination，ventriculomegaly and intracranial calcifications.
来源： Human Cells

其它标识

内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

产品介绍 Product Introduction

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注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
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