Recombinant Human Sialate O-acetylesterase/SIAE,BR

产品属性 Product Attributes

基本信息

别名： Sialate O-Acetylesterase;H-Lse;Sialic Acid-Specific 9-O-Acetylesterase;SIAE;YSG2
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Supplied as a 0.2 μm filtered solution of 20mM TrisHCl,150mM NaCl,10%Glycerol,pH7.5.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

产品信息

背景说明： Sialate O-Acetylesterase (SIAE) belongs to the family of hydrolases，specifically those acting on carboxylic ester bonds.SIAE is widely expressed with high expression levels in the testis，prostate，and colon.SIAE catalyzes N-acetyl-O-acetylneuraminate and H2O to N-acetylneuraminate and acetate.SIAE removes O-acetyl ester groups from position 9 of the parent sialic acid，N-acetylneuraminic acid.SIAE down-regulates B lymphocyte antigen receptor signaling (involving CD22)，and is required for immunological tolerance.Loss of function mutations in SIAE are much more frequently found in humans with autoimmune diseases especially rheumatoid arthritis and type 1 diabetes.
来源： Human Cells

其它标识

内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

产品介绍 Product Introduction

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注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
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3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。