Recombinant Human Hepatocyte cell adhesion molecule/HepaCAM,BR

产品属性 Product Attributes

基本信息

别名： Hepatocyte Cell Adhesion Molecule;Protein HepaCAM;HEPACAM
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： Hepatocyte Cell Adhesion Molecule (HEPACAM) is a single-pass type I membrane protein that localizes to the cytoplasmic side of the cell membrane.HEPACAM includes a signal sequence (amino acid 1-33)，an extracellular region (amino acid 34-240) with one Ig-like C2-type domain and one Ig-like V-type domain，a transmembrane segment (amino acid 241-261)，and a cytoplasmic domain (amino acid 262 - 416).The cytoplasmic domain plays an important role in regulation of cell-matrix adhesion and cell motility.HEPACAM acts as a homodimer and dimer formation occurs predominantly through cis interactions on the cell surface.HEPACAM is involved in cell motility and cell-matrix interactions.The expression of this gene is down-regulated or undetectable in many cancer cell lines，so this may be a tumor suppressor gene.
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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