Recombin human SPAM1 protein,BR

产品属性 Product Attributes

基本信息

基因名: SPAM1
别名: epididymis secretory sperm binding protein Li 96n;HEL-S-96n;HYA1;HYAL PH-20;HYAL PH20;Hyal-PH20;HYAL1;HYAL3;HYAL5;HYALP_HUMAN;Hyaluronidase PH-20;Hyaluronoglucosaminidase PH-20;MGC26532;PH-20 Hyaluronidase;PH20;PH20 Hyaluronidase;SPAG15;SPAM-1;Spam1;sperm adhesion molecule 1 (PH-20 hyaluronidase，zona pellucida binding);Sperm adhesion molecule 1;Sperm surface protein PH-20;Sperm surface protein PH20;zona pellucida binding;
全名: sperm adhesion molecule 1 (PH-20 hyaluronidase，zona pellucida binding)
英文名称: Recombinant human SPAM1 protein
中文名称: 精子粘附分子1
规格: 10ug ; 50ug ; 100ug ; 1mg
外观:(性状) Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. (Or liquid with 5% glycerol.)
纯度: ≥85% by SDS-PAGE.
储存条件: Reconstituted protein solution can be stored at 4-7°C for 1-2 weeks, stored at < -20°C for 1 year.
运输条件: The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below.
浓度: 1mg/ml by SDS-PAGE.

产品信息

Swiss Prot： P38567
Gene ID： 6677
交叉反应： Human Mouse Rat (Pig Monkey)
分子量： 40kDa
区间范围： 141-490aa
背景说明： Hyaluronidase degrades hyaluronic acid, a major structural proteoglycan found in extracellular matrices and basement membranes. Six members of the hyaluronidase family are clustered into two tightly linked groups on chromosome 3p21.3 and 7q31.3. This gene was previously referred to as HYAL1 and HYA1 and has since been assigned the official symbol SPAM1; another family member on chromosome 3p21.3 has been assigned HYAL1. This gene encodes a GPI-anchored enzyme located on the human sperm surface and inner acrosomal membrane. This multifunctional protein is a hyaluronidase that enables sperm to penetrate through the hyaluronic acid-rich cumulus cell layer surrounding the oocyte, a receptor that plays a role in hyaluronic acid induced cell signaling, and a receptor that is involved in sperm-zona pellucida adhesion. Abnormal expression of this gene in tumors has implicated this protein in degradation of basement membranes leading to tumor invasion and metastasis. Multiple transcript variants encoding different isoforms have been found for this gene.
应用： Immunology research
来源： E.coli

其它标识

纯化方法： NI-NTA affinity purification
溶剂： Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.)
内毒素： Not measured
生物活性： N0
标签信息： With a 6×His tag at the N/C-terminus.

产品介绍 Product Introduction

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注意事项 Considerations

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