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- Recombinant Human TNFSF10/TRAIL/APO-2L,BR
Recombinant Human TNFSF10/TRAIL/APO-2L,BR
Recombinant Human TNFSF10/TRAIL/APO-2L
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Known as:Tumor Necrosis Factor Ligand Superfamily Member 10; Apo-2 Ligand; Apo-2L; TNF-Related Apoptosis-Inducing Ligand; Protein TRAIL; CD253; TNFSF10; APO2L; TRAIL
Derived from:E.coli
Purity:Greater than 95% as determined by reducing SDS-PAGE.
Formulation:Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 20% Glycerol, 150mM Nacl, 1mM EDTA, pH8.0.
Storage:Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening.Please minimize freeze-thaw cycles.
Endotoxin:Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.
Background:Human TNFSF10 is a type II transmembrane protein with an intracellular N-terminus and a ‘TNF homology domain’ (THD) at the extracellular C terminus. TNFSF10 can interact with several distinct receptors. Two of these receptors that belongs to TNFR superfamily, DR4 (TRAIL-R1) and DR5 (TRAIL-R2/TRICK2), are plasma membrane proteins containing intracellular death domains essential for activating apoptosis. TNFSF10 is promising for cancer therapy because it is cytotoxic and activates apoptosis in the majority of malignant cells, but not in normal cells.
规格:10ug, 50ug, 500ug, 1mg, 注意:
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