Recombinant Mouse Fc gamma RIV/FcgR4/CD16-2/Low Affinity IgG Fc Region Receptor IV,BR

产品属性 Product Attributes

基本信息

别名： Low Affinity Immunoglobulin Gamma Fc Region Receptor IV;FcgR4;CD16-2
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： Fcgr4，also known as CD16-2，is one of the receptors for Fc region of IgG which involve in immune responses.Fcgr4 mainly functions in cellular response to lipopolysaccharide，NK T cell proliferation，regulation of sensory perception of pain，wound healing etc.Three groups are included for Fc γ receptors (FcR)，and they are Fc γ RI (CD64)，Fc γ RII (CD32)，and Fc γ RIII (CD16).Among these，CD64 possess high affinity even for monomeric IgG，while CD32 and CD16 display a relative lower affinity for IgG.Genes encodes these receptors are diverse differing by species and cell types.The aggregation of FcR having immunoreceptor tyrosine-based activation motifs (ITAMs) activates sequentially src family tyrosine kinases and syk family tyrosine kinases that connect transduced signals to common activation pathways shared with other receptors.FcR with ITAMs elicit cell activation，endocytosis，and phagocytosis.Fcgr4 belongs to Fc γ RIII (CD16) group.
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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