Recombinant Mouse Thrombomodulin/BDCA-3/CD141,BR

产品属性 Product Attributes

基本信息

别名： Thrombomodulin;TM;Fetomodulin;CD141;BDCA-3;Thbd
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH8.0.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

产品信息

背景说明： Thrombomodulin is also known as CD141 antigen and blood dendritic cell antigen 3 (BDCA3)，which is encoded by the THBD gene.The deduced amino acid sequence of mouse THBD predicts a signal peptide (aa 1 to 16) and a mature chain (aa 17 to 577) that consists of the following domains: C-type lectin，EGF-like，transmembrane and cytoplasmic.Mouse THBD is corresponding to the extracellular portion of the type I membrane protein.Predominantly synthesized by vascular endothelial cells，THBD inhibits coagulation and fibrinolysis.It functions as a cell surface receptor and an essential cofactor for active thrombin，which in turn activates protein C and thrombinactivatable fibrinolysis inhibitor (TAFI)，also known as carboxypeptidase B2 (CPB2).In addition，THBD gene polymorphisims are associated with human disease and THBD plays a role in thrombosis，stroke，arteriosclerosis，and cancer.
来源： Human Cells

其它标识

内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

产品介绍 Product Introduction

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注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
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3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。